Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Family-based association between Alzheimer's disease and variants in UBQLN1.

The New England journal of medicine - 3 Mar 2005

Bertram Lars, Hiltunen Mikko, Parkinson Michele, Ingelsson Martin, Lange Christoph, Ramasamy Karunya, Mullin Kristina, Menon Rashmi, Sampson Andrew J, Hsiao Monica Y, Elliott Kathryn J, Velicelebi Gonül, Moscarillo Thomas, Hyman Bradley T, Wagner Steven L, Becker K David, Blacker Deborah, Tanzi Rudolph E

Abstract excerpt

BACKGROUND: Recent analyses suggest that the known Alzheimer's disease genes account for less than half the genetic variance in this disease. The gene encoding ubiquilin 1 (UBQLN1) is one of several candidate genes for Alzheimer's disease located near a well-established linkage peak on chromosome...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter 1

Share to ATP-Binding Cassette Transporters

Share to Autophagy-Related Proteins

Share to Cell Cycle Proteins

Share to Chromosomes, Human, Pair 9

Share to Logistic Models

Source

Identifiers

PMID: 15745979
DOI: 10.1056/NEJMoa042765

Genes

UBQLN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15745979-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Family-based association between Alzheimer's disease and variants in UBQLN1.PMID 15745979Read ↗

Genetic association of ubiquilin with Alzheimer's disease and related quantitative measures.Semantic proximity Read ↗

Meta-analysis of Ubiquilin1 gene polymorphism and Alzheimer's disease risk.Semantic proximity Read ↗

Lack of association between UBQLN1 and Alzheimer disease.Semantic proximity Read ↗

Analyses of the National Institute on Aging Late-Onset Alzheimer's Disease Family Study: implication of additional loci.Semantic proximity Read ↗

Relationship of the Ubiquilin 1 gene with Alzheimer's and Parkinson's disease and cognitive function.Semantic proximity Read ↗

Ubiquilin-1 Is a Molecular Chaperone for the Amyloid Precursor ProteinSemantic proximity Read ↗

Analysis of UBQLN1 variants in a Polish Alzheimer's disease patient: control series.Semantic proximity Read ↗

The UBQLN1 polymorphism, UBQ-8i, at 9q22 is not associated with Alzheimer's disease with onset before 70 years.Semantic proximity Read ↗

The association between the UBQLN1 polymorphism and Alzheimer's disease risk: A systematic review.Semantic proximity Read ↗

Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease.Semantic proximity Read ↗

Association of UBQ-8i polymorphism with Alzheimer's disease in Caucasians: a meta-analysis.Semantic proximity Read ↗

Linkage and association study of late-onset Alzheimer disease families linked to 9p21.3.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.