Article
No association between SNP rs498055 on chromosome 10 and late-onset Alzheimer disease in multiple datasets.
Annals of human genetics - 1 Jan 2008
Liang Xueying, Schnetz-Boutaud Nathalie, Bartlett Jackie, Allen Melissa J, Gwirtsman Harry, Schmechel Don E, Carney Regina M, Gilbert John R, Pericak-Vance Margaret A, Haines Jonathan L
Abstract excerpt
SNP rs498055 in the predicted gene LOC439999 on chromosome 10 was recently identified as being strongly associated with late-onset Alzheimer disease (LOAD). This SNP falls within a chromosomal region that has engendered continued interest generated from both preliminary genetic linkage and candidate gene studies. To independently evaluate this interesting candidate SNP we examined four independent datasets, three...
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