Article
Association of ABCA1 with late-onset Alzheimer's disease is not observed in a case-control study.
Neuroscience letters - 19 Aug 2004
Li Yonghong, Tacey Kristina, Doil Lisa, van Luchene Ryan, Garcia Veronica, Rowland Charles, Schrodi Steve, Leong Diane, Lau Kit, Catanese Joe, Sninsky John, Nowotny Petra, Holmans Peter, Hardy John, Powell John, Lovestone Simon, Thal Leon, Owen Michael, Williams Julie, Goate Alison, Grupe Andrew
Abstract excerpt
Genetic association of ABCA1 or the ATP-binding cassette A1 transporter with late-onset Alzheimer's disease (LOAD) has recently been proposed for a haplotype comprised of three single nucleotide polymorphisms (SNPs). We have genotyped these and other ABCA1 SNPs in a LOAD case-control series of 796 individuals (419 cases versus 377 controls) collected at Washington University. While our sample series is larger and...
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