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Article

Chemokine C receptor 7 expression and protection of circulating CD8+ T lymphocytes from apoptosis.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2005

Kim Jeong-Whun, Ferris Robert L, Whiteside Theresa L

Abstract excerpt

Chemokine C receptor 7 (CCR7) expression is important for lymphocyte homing to tissues. We hypothesized that CCR7 also plays a role in CD8(+) T-cell protection from apoptosis. Its expression was determined on circulating T cells in patients with cancer and related to that of molecules responsible for lymphocyte susceptibility/resistance to apoptosis. Peripheral blood mononuclear cells were obtained from 36...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16278415
DOI: 10.1158/1078-0432.CCR-05-1346

Genes

CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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