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Article

Identification and characterization of a mammalian 39-kDa poly(ADP-ribose) glycohydrolase.

The Journal of biological chemistry - 13 Jan 2006

Oka Shunya, Kato Jiro, Moss Joel

Abstract excerpt

ADP-ribosylation is a post-translational modification resulting from transfer of the ADP-ribose moiety of NAD to protein. Mammalian cells contain mono-ADP-ribosyltransferases that catalyze the formation of ADP-ribose-(arginine) protein, which can be cleaved by a 39-kDa ADP-ribose-(arginine) protein hydrolase (ARH1), resulting in release of free ADP-ribose and regeneration of unmodified protein. Enzymes involved...

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Source

Identifiers

PMID: 16278211
DOI: 10.1074/jbc.M510290200

Genes

PARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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