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ADP-Ribosylation as Post-Translational Modification of Proteins: Use of Inhibitors in Cancer Control

7 Oct 2021

Abstract excerpt

Among the post-translational modifications of proteins, ADP-ribosylation has been studied for over fifty years, and a large set of functions, including DNA repair, transcription, and cell signaling, have been assigned to this post-translational modification (PTM). This review presents an update on the function of a large set of enzyme writers, the readers that are recruited by the modified targets, and the...

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PMID: 34639169
DOI: 10.3390/ijms221910829

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