Article
P53 alteration in oral tongue cancer is not significantly associated with age at diagnosis or tobacco exposure.
Tumori - 1 Jan 2000
Siegelmann-Danieli Nava, Ben-Izhack Ofer, Hanlon Alexandra, Ridge John A, Stein Moshe E, Khandelwal Vivek, Langer Corey J
Abstract excerpt
AIMS AND BACKGROUND: The tumor suppressor gene P53 is mutated in almost half of head and neck cancers. The current work assessed the prognostic significance of P53 alteration in patients with squamous cell carcinoma of the oral tongue treated with a curative intent, its association with age at diagnosis (using 45 years as a cut point), and risk exposure as defined by tobacco and/or alcohol consumption. METHODS:...
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