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Article

APOE polymorphism is associated with risk of severe sepsis in surgical patients.

Critical care medicine - 1 Nov 2005

Moretti Eugene W, Morris Richard W, Podgoreanu Mihai, Schwinn Debra A, Newman Mark F, Bennett Ellen, Moulin Victor G, Mba Uzo U, Laskowitz Daniel T

Abstract excerpt

OBJECTIVE: To test for an association between apolipoprotein E (APOE) genotypes and the occurrence of severe sepsis in an elective surgical cohort. DESIGN: Prospective, observational, single cohort study. SETTING: Sixteen-bed surgical intensive care unit (ICU) at a university hospital. PATIENTS: Patients were 343 patients with planned admission to the ICU after major elective noncardiac surgery. INTERVENTIONS:...

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Source

Identifiers

PMID: 16276176
DOI: 10.1097/01.ccm.0000186368.96146.fb

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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