Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cholesteryl Ester Transfer Protein Influences High-Density Lipoprotein Levels and Survival in Sepsis

15 Oct 2018

Abstract excerpt

RATIONALE: High-density lipoprotein (HDL) cholesterol (HDL-C) levels decline during sepsis, and lower levels are associated with worse survival. However, the genetic mechanisms underlying changes in HDL-C during sepsis, and whether the relationship with survival is causative, are largely unknown. OBJECTIVES: We hypothesized that variation in genes involved in HDL metabolism would contribute to changes in HDL-C...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hyperglycemia and glycemic control in critically ill and hospitalized patients
Share to Immune Response and Inflammation
Share to Sepsis Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30321485
DOI: 10.1164/rccm.201806-1157oc

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cholesteryl Ester Transfer Protein Influences High-Density Lipoprotein Levels and Survival in SepsisPMID 30321485Read ↗

CETP genetic variant rs1800777 (allele A) is associated with abnormally low HDL-C levels and increased risk of AKI during sepsisSemantic proximity Read ↗

Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis.Semantic proximity Read ↗

A comprehensive understanding of HDL-associated apolipoproteins: future potential biomarker in sepsis.Semantic proximity Read ↗

Genetic insights into cholesteryl ester transfer protein as a novel therapeutic target for sepsis and severe pneumoniaSemantic proximity Read ↗

A hypolipoprotein sepsis phenotype indicates reduced lipoprotein antioxidant capacity, increased endothelial dysfunction and organ failure, and worse clinical outcomes.Semantic proximity Read ↗

Identification of a nonsynonymous polymorphism in the SVEP1 gene associated with altered clinical outcomes in septic shock.Semantic proximity Read ↗

Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study.Semantic proximity Read ↗

Genetic insights into sepsis: what have we learned and how will it help?Semantic proximity Read ↗

Multiomic molecular patterns of lipid dysregulation in a subphenotype of sepsis with higher shock incidence and mortality.Semantic proximity Read ↗

Elevated plasma cholesterol causally improves sepsis outcome by promoting hepatic metabolic reprogrammingSemantic proximity Read ↗

Leucyl/cystinyl aminopeptidase gene variants in septic shock.Semantic proximity Read ↗

SERPINE1 rs1799768 polymorphism contributes to sepsis risk and mortality.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.