Article
Apolipoprotein E4 polymorphism as a genetic predisposition to delirium in critically ill patients.
Critical care medicine - 1 Jan 2007
Ely E Wesley, Girard Timothy D, Shintani Ayumi K, Jackson James C, Gordon Sharon M, Thomason Jason W W, Pun Brenda T, Canonico Angelo E, Light Richard W, Pandharipande Pratik, Laskowitz Daniel T
Abstract excerpt
OBJECTIVE: To test for an association between apolipoprotein E (APOE) genotypes and duration of intensive care unit delirium. DESIGN: Prospective, observational cohort study. SETTING: A 541-bed, community-based teaching hospital. PATIENTS: Fifty-three mechanically ventilated intensive care unit patients. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: All patients were managed with standardized sedation and...
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