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Article

Histone Variant H3.3: A versatile H3 variant in health and in disease.

Science China. Life sciences - 1 Mar 2016

Xiong Chaoyang, Wen Zengqi, Li Guohong

Abstract excerpt

Histones are the main protein components of eukaryotic chromatin. Histone variants and histone modifications modulate chromatin structure, ensuring the precise operation of cellular processes associated with genomic DNA. H3.3, an ancient and conserved H3 variant, differs from its canonical H3 counterpart by only five amino acids, yet it plays essential and specific roles in gene transcription, DNA repair and in...

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Identifiers

PMID: 26825948
DOI: 10.1007/s11427-016-5006-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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