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Article

Single base mismatch detection by microsecond voltage pulses.

Biosensors & bioelectronics - 15 Dec 2005

Fixe F, Chu V, Prazeres D M F, Conde J P

Abstract excerpt

A single square voltage pulse applied to metal electrodes underneath a silicon dioxide film upon which DNA probes are immobilized allows the discrimination of DNA targets with a single base mismatch during hybridization. Pulse duration, magnitude and slew rate of the voltage pulse are all key factors controlling the rates of electric field assisted hybridization. Although pulses with 1 V, lasting less than 1 ms...

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Share to Base Pair Mismatch
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 16257657
DOI: 10.1016/j.bios.2005.02.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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