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Article

Study of single-nucleotide polymorphisms by means of electrical conductance measurements.

Proceedings of the National Academy of Sciences of the United States of America - 22 Nov 2005

Hihath Joshua, Xu Bingqian, Zhang Peiming, Tao Nongjian

Abstract excerpt

Understanding the complexities of DNA has been a hallmark of science for over a half century, and one of the important topics in DNA research is recognizing the occurrence of mutations in the base-stack. In this article, we present a study of SNPs by direct-contact electrical measurements to a single DNA duplex. We have used short, 11- and 12-bp dsDNA to investigate the change in conductance that occurs if a...

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Identifiers

PMID: 16284253
DOI: 10.1073/pnas.0505175102
PMCID: PMC1287980

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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