Article
Sequential DNA hybridisation assays by fast micromixing.
Lab on a chip - 1 Oct 2004
Heule Martin, Manz Andreas
Abstract excerpt
The prospects of performing DNA hybridisation assays in a novel sequential scheme are explored in this article. It is based on recording the kinetics of hybridisation on a microfluidic device measuring only 10 by 5 mm. It contains a split channel system for fast mixing and a subsequent meandering channel to observe the evolution of the mixture by optical means. The problems of diffusion limitations in the laminar...
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