Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of oligonucleotide systematic mismatches with a surface plasmon resonance sensor.

Biosensors & bioelectronics - 15 Jan 2010

Milkani Eftim, Morais Sergi, Lambert Christopher R, McGimpsey W Grant

Abstract excerpt

The detection and parallel characterization of the hybridization event of 21-base, unlabeled DNA oligonucleotides with a monolayer of complementary DNA immobilized on a gold surface by surface plasmon resonance (SPR) is presented. A thiol modification on the probe DNA strand allowed for its attachment to the surface via self-assembly. For the hybridization of full match DNA a detection limit of 20 pM was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Pair Mismatch
Share to Biosensing Techniques
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Equipment Design

Share to Reproducibility of Results

Share to Sensitivity and Specificity

Share to Surface Plasmon Resonance

Source

Identifiers

PMID: 19819685
DOI: 10.1016/j.bios.2009.09.010

Genes

SPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of oligonucleotide systematic mismatches with a surface plasmon resonance sensor.PMID 19819685Read ↗

Kinetic discrimination of DNA single-base mutations by localized surface plasmon resonance.Semantic proximity Read ↗

Scanning positional variations in single-nucleotide polymorphism of DNA: an electrochemical study.Semantic proximity Read ↗

Scanning of guanine-guanine mismatches in DNA by synthetic ligands using surface plasmon resonance.Semantic proximity Read ↗

Label-free detection of DNA mutations by SPR: application to the early detection of inherited breast cancer.Semantic proximity Read ↗

DNA single-base mismatch study with an electrochemical enzymatic genosensor.Semantic proximity Read ↗

Femtomolar oligonucleotide detection by a one-step gold nanoparticle-based assay.Semantic proximity Read ↗

Preparation and use of metal surface-immobilized DNA hairpins for the detection of oligonucleotides.Semantic proximity Read ↗

Influence of the length of target DNA overhang proximal to the array surface on discrimination of single-base mismatches on a 25-mer oligonucleotide array.Semantic proximity Read ↗

DNA biosensor based on hybridization refractory mutation system approach for single mismatch detection.Semantic proximity Read ↗

Single nucleotide mismatch analysis using oligonucleotide probes synthesized on bacterial magnetic particle.Semantic proximity Read ↗

Cantilever-based optical deflection assay for discrimination of DNA single-nucleotide mismatches.Semantic proximity Read ↗

Exploiting the interactions of PNA-DNA films with Ni2+ ions: detection of nucleobase mismatches and electrochemical genotyping of the single-nucleotide mismatch in apoE 4 related to Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.