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Article

Viral load change and sequential evolution of entire hepatitis C virus genome in Irish recipients of single source-contaminated anti-D immunoglobulin*.

Journal of viral hepatitis - 1 Nov 2005

Itakura J, Nagayama K, Enomoto N, Hamano K, Sakamoto N, Fanning L J, Kenny-Walsh E, Shanahan F, Watanabe M

Abstract excerpt

In hepatitis C virus (HCV) infection, serum viral load is important in the prediction of therapeutic efficacy. However, factors that affect the viral load remain poorly understood. To identify viral genomic elements responsible for the viral load, we investigated samples from a population of Irish women who were iatrogenically infected from a single HCV source by administration of HCV 1b-contaminated anti-D...

Topics

Amino Acid Sequence
Drug Contamination
Evolution, Molecular
Female
Genome, Viral
Hepacivirus
Hepatitis C
Humans
Immunologic Factors
Ireland
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Phylogeny

Rho(D) Immune Globulin

Sequence Analysis, DNA

Viral Load

Source

Identifiers

PMID: 16255760
DOI: 10.1111/j.1365-2893.2005.00645.x

Provenance

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