Dynamic changes in hepatitis C virus genotypes and sequence patterns in plasma donors exposed to reinfection.

doi:10.1002/1096-9071(200103)63:3<228::aid-jmv1005>3.0.co;2-t

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Article

Dynamic changes in hepatitis C virus genotypes and sequence patterns in plasma donors exposed to reinfection.

Journal of medical virology - 1 Mar 2001

Zhang S, Hui Z, Li H, Qi Z, Widell A

Abstract excerpt

Sequential serum samples from four plasma donors (designated A, B, C, and D) at a Chinese blood bank with hepatitis C transmission problems were studied from 1994 to 1997. The samples were examined for antibodies to HCV, for HCV viremia by PCR and HCV genotyping. Co- and superinfections were studied by direct sequencing of the 5'-NCR, core, and HVR-1 regions, using low and high genotype-specific primers targeting...

Topics

Blood Banks
Blood Donors
Blood Specimen Collection
Cloning, Molecular
Cross Infection
Genotype
Hepacivirus
Hepatitis C
Hepatitis C Antibodies
Humans
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phylogeny

Polymerase Chain Reaction

RNA, Viral

Recurrence

Viral Core Proteins

Viral Envelope Proteins

Source

Open in PubMed

Identifiers

PMID: 11170062
DOI: 10.1002/1096-9071(200103)63:3<228::aid-jmv1005>3.0.co;2-t

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