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Article

Sequence variability in the env-coding region of hepatitis C virus isolated from patients infected during a single source outbreak.

Archives of virology - 1 Jan 1994

Höhne M, Schreier E, Roggendorf M

Abstract excerpt

The variability of the hepatitis C virus genome was investigated in a group of German patients who developed chronic hepatitis C after parenteral administration of contaminated immunoglobulin to prevent Rh sensitization after pregnancy. The nucleotide and deduced amino acid sequence alterations of the E1 and the first hypervariable region of the E2 gene of the hepatitis C virus (HCV) genome from sera of two...

Topics

Amino Acid Sequence
Base Sequence
DNA Primers
DNA, Complementary
Disease Outbreaks
Gene Products, env
Genes, env
Genetic Variation
Germany
Hepacivirus
Hepatitis C

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Molecular Sequence Data

Polymerase Chain Reaction

RNA, Viral

Sequence Homology, Amino Acid

Source

Identifiers

PMID: 7979995
DOI: 10.1007/BF01311170

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7979995-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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