Article
The origin of hepatitis C virus genotypes.
The Journal of general virology - 1 Feb 1997
Smith D B, Pathirana S, Davidson F, Lawlor E, Power J, Yap P L, Simmonds P
Abstract excerpt
For many RNA viruses, relatively recent times of origin of extant viruses are implied by the high rate of substitution observed in longitudinal studies. However, extrapolation of short-term rates of substitution can give misleading estimates of times of divergence. We show here that the common an...
Topics
- Antibodies, Anti-Idiotypic
- Cohort Studies
- Evolution, Molecular
- Genome, Viral
- Genotype
- Hepacivirus
- Hepatitis C
- Humans
- Immunoglobulin D