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Article

High-resolution whole-genome association study of Parkinson disease.

American journal of human genetics - 1 Nov 2005

Maraganore Demetrius M, de Andrade Mariza, Lesnick Timothy G, Strain Kari J, Farrer Matthew J, Rocca Walter A, Pant P V Krishna, Frazer Kelly A, Cox David R, Ballinger Dennis G

Abstract excerpt

We performed a two-tiered, whole-genome association study of Parkinson disease (PD). For tier 1, we individually genotyped 198,345 uniformly spaced and informative single-nucleotide polymorphisms (SNPs) in 443 sibling pairs discordant for PD. For tier 2a, we individually genotyped 1,793 PD-associated SNPs (P<.01 in tier 1) and 300 genomic control SNPs in 332 matched case-unrelated control pairs. We identified 11...

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Identifiers

PMID: 16252231
DOI: 10.1086/496902
PMCID: PMC1271381

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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