Article
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
PLoS genetics - 1 Jun 2011
Do Chuong B, Tung Joyce Y, Dorfman Elizabeth, Kiefer Amy K, Drabant Emily M, Francke Uta, Mountain Joanna L, Goldman Samuel M, Tanner Caroline M, Langston J William, Wojcicki Anne, Eriksson Nicholas
Abstract excerpt
Although the causes of Parkinson's disease (PD) are thought to be primarily environmental, recent studies suggest that a number of genes influence susceptibility. Using targeted case recruitment and online survey instruments, we conducted the largest case-control genome-wide association study (GWAS) of PD based on a single collection of individuals to date (3,426 cases and 29,624 controls). We discovered two...
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