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Article

p53 Codon 72 polymorphism predicts the pathologic response to neoadjuvant chemotherapy in patients with breast cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2005

Xu Ye, Yao Lihua, Ouyang Tao, Li Jinfeng, Wang Tianfeng, Fan Zhaoqing, Lin Benyao, Lu Youyong, Xie Yuntao

Abstract excerpt

PURPOSE: Recent studies have highlighted that the p53 codon 72 polymorphism plays a crucial role in modulating wild-type p53 apoptotic capacity, and as such may influence the response to chemotherapy. Thus, the purpose of this study was to investigate whether the p53 codon 72 polymorphism might influence pathologic response to neoadjuvant chemotherapy in primary breast cancer. EXPERIMENTAL DESIGN: One hundred and...

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Identifiers

PMID: 16243804
DOI: 10.1158/1078-0432.CCR-05-0507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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