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Breast cancer patients with p53 Pro72 homozygous genotype have a poorer survival.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2005

Tommiska Johanna, Eerola Hannaleena, Heinonen Mira, Salonen Laura, Kaare Milja, Tallila Jonna, Ristimäki Ari, von Smitten Karl, Aittomäki Kristiina, Heikkilä Päivi, Blomqvist Carl, Nevanlinna Heli

Abstract excerpt

PURPOSE: The p53 R72P polymorphism has been suggested to play a role in many cancers, including breast cancer. Our aim was to evaluate association of R72P with breast cancer risk as well as histopathologic features of the breast tumors and survival. EXPERIMENTAL DESIGN: The germ line R72P genotype was defined among 939 Finnish familial and 888 unselected breast cancer patients and 736 healthy population controls....

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PMID: 16033823
DOI: 10.1158/1078-0432.CCR-05-0173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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