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Article

Effect of p53 codon 72 genotype on breast cancer survival depends on p53 gene status.

International journal of cancer - 15 Jun 2008

Xu Ye, Yao Lihua, Zhao Ailian, Ouyang Tao, Li Jinfeng, Wang Tianfeng, Fan Zhaoqing, Fan Tie, Lin Benyao, Lu Youyong, Xie Yuntao

Abstract excerpt

In vitro studies suggest that p53 codon 72 genotype alters the apoptotic capacity of p53 protein, with the 72 arginine (R) form of wild-type p53 harboring a greater apoptosis-inducing potential than the 72 proline (P) variant. The aim of this study was to investigate whether the association between the p53 codon 72 genotype and breast cancer survival was modified by p53 gene status. In our study, we examined the...

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PMID: 18348141
DOI: 10.1002/ijc.23454

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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