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Article

The spectrum of cardiovascular anomalies in CHF1/Hey2 deficient mice reveals roles in endocardial cushion, myocardial and vascular maturation.

Journal of molecular and cellular cardiology - 1 Feb 2006

Sakata Yasuhiko, Koibuchi Nobutaka, Xiang Fan, Youngblood Joey M, Kamei Caramai N, Chin Michael T

Abstract excerpt

CHF1/Hey2 null mice generated in different laboratories have discrepant cardiovascular phenotypes. To determine the effect of genetic background on phenotype, we backcrossed our knockout strain more than eight generations to the inbred strains BALB/c and C57BL/6. Knockout mice on these backgrounds showed disparate phenotypes. Mice on both backgrounds demonstrated ventricular septal defects (VSDs), tricuspid...

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Identifiers

PMID: 16242143
DOI: 10.1016/j.yjmcc.2005.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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