Article
A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse.
Journal of visualized experiments : JoVE - 16 Dec 2022
Guzman-Moreno Carla, Zhang Peizhao, Phillips Olivia R, Block Mathias, Glennon Benjamin J, Holbrook Meghan, Weigand Lauren, Lo Cecilia W, Lin Jiuann-Huey I
Abstract excerpt
Congenital heart diseases (CHDs) are major causes of infant death in the United States. In the 1980s and earlier, most patients with moderate or severe CHD died before adulthood, with the maximum mortality during the first week of life. Remarkable advances in surgical techniques, diagnostic approaches, and medical management have led to marked improvements in outcomes. To address the critical research needs of...
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