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Article

Early myocardial function affects endocardial cushion development in zebrafish.

PLoS biology - 1 May 2004

Bartman Thomas, Walsh Emily C, Wen Kuo-Kuang, McKane Melissa, Ren Jihui, Alexander Jonathan, Rubenstein Peter A, Stainier Didier Y R

Abstract excerpt

Function of the heart begins long before its formation is complete. Analyses in mouse and zebrafish have shown that myocardial function is not required for early steps of organogenesis, such as formation of the heart tube or chamber specification. However, whether myocardial function is required for later steps of cardiac development, such as endocardial cushion (EC) formation, has not been established. Recent...

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Identifiers

PMID: 15138499
DOI: 10.1371/journal.pbio.0020129
PMCID: PMC406391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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