Article
Analysis of the kinetics of the membrane potential generated by cytochrome c oxidase upon single electron injection.
Biochimica et biophysica acta - 15 Nov 2005
Medvedev D M, Medvedev E S, Kotelnikov A I, Stuchebrukhov A A
Abstract excerpt
In a recent work from this group (Popovic, D. M.; Stuchebrukhov A. A. FEBS Lett. 2004, 566, 126), a model of proton pumping by cytochrome c oxidase (CcO) was proposed. The key element of the model is His291 (bovine notation), a histidine ligand to enzyme's CuB redox center, which plays the role of the pump element. The model assumes that upon electron transfer between heme a and the binuclear catalytic center of...
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