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Article

Cytochrome c oxidase: exciting progress and remaining mysteries.

Journal of bioenergetics and biomembranes - 1 Oct 2008

Brzezinski Peter, Gennis Robert B

Abstract excerpt

Cytochrome c oxidase generates a proton motive force by two separate mechanisms. The first mechanism is similar to that postulated by Peter Mitchell, and is based on electrons and protons used to generate water coming from opposite sides of the membrane. The second mechanism was not initially anticipated, but is now firmly established as a proton pump. A brief review of the current state of our understanding of...

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Identifiers

PMID: 18975062
DOI: 10.1007/s10863-008-9181-7
PMCID: PMC4012550

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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