Article
The C. elegans RUNX transcription factor RNT-1/MAB-2 is required for asymmetrical cell division of the T blast cell.
Developmental biology - 15 Nov 2005
Kagoshima Hiroshi, Sawa Hitoshi, Mitani Shohei, Bürglin Thomas R, Shigesada Katsuya, Kohara Yuji
Abstract excerpt
The RUNX genes encode conserved transcription factors, which play vital roles in the development of various animals and human diseases. Drosophila runt is a secondary pair-rule gene, which regulates embryo segmentation. Human RUNX1, previously known as AML1, is essential for hematopoiesis. C. elegans rnt-1 is co-orthologous to the human RUNX genes. We found that RNT-1Colon, two colonsGFP is expressed in the H0-2,...
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