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RNT-1, the C. elegans homologue of mammalian RUNX transcription factors, regulates body size and male tail development.

Developmental biology - 15 Oct 2004

Ji Yon-Ju, Nam Seunghee, Jin Yun-Hye, Cha Eun-Jung, Lee Kyeong-Sook, Choi Kyu-Yeong, Song Hyun-Ok, Lee Junho, Bae Suk-Chul, Ahnn Joohong

Abstract excerpt

The rnt-1 gene is the only Caenorhabditis elegans homologue of the mammalian RUNX genes. Several lines of molecular biological evidence have demonstrated that the RUNX proteins interact and cooperate with Smads, which are transforming growth factor-beta (TGF-beta) signal mediators. However, the involvement of RUNX in TGF-beta signaling has not yet been supported by any genetic evidence. The Sma/Mab TGF-beta...

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PMID: 15385167
DOI: 10.1016/j.ydbio.2004.07.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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