Article
A novel noncanonical Wnt pathway is involved in the regulation of the asymmetric B cell division in C. elegans.
Developmental biology - 15 May 2006
Wu Mingfu, Herman Michael A
Abstract excerpt
The polarities of several cells that divide asymmetrically during Caenorhabditis elegans development are controlled by Wnt signaling. LIN-44/Wnt and LIN-17/Fz control the polarities of cells in the tail of developing C. elegans larvae, including the male-specific blast cell, B, that divides asymmetrically to generate a larger anterior daughter and a smaller posterior daughter. We determined that WRM-1 and the...
Topics
- Actins
- Animals
- Animals, Genetically Modified
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Division
- Cell Polarity
- Genes, Helminth
- Intracellular Signaling Peptides and Proteins
- Models, Biological
- Mutation
- Protein Serine-Threonine Kinases
- RNA Interference
- Signal Transduction
- Wnt Proteins
- rho-Associated Kinases
- rhoA GTP-Binding Protein