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Article

Components of the transcriptional Mediator complex are required for asymmetric cell division in C. elegans.

Development (Cambridge, England) - 1 Apr 2005

Yoda Akinori, Kouike Hiroko, Okano Hideyuki, Sawa Hitoshi

Abstract excerpt

Asymmetric cell division is a fundamental process that produces cellular diversity during development. In C. elegans, the Wnt signaling pathway regulates the asymmetric divisions of a number of cells including the T blast cell. We found that the let-19 and dpy-22 mutants have defects in their T-cell lineage, and lineage analyses showed that the defects were caused by disruption in the asymmetry of the T-cell...

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Identifiers

PMID: 15790964
DOI: 10.1242/dev.01776

Genes

MED12
MED13
MED23
MED6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Components of the transcriptional Mediator complex are required for asymmetric cell division in C. elegans.PMID 15790964Read ↗

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