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Article

Mutation in APOA1 predicts increased risk of ischaemic heart disease and total mortality without low HDL cholesterol levels.

Journal of internal medicine - 1 Aug 2011

Haase C L, Frikke-Schmidt R, Nordestgaard B G, Kateifides A K, Kardassis D, Nielsen L B, Andersen C B, Køber L, Johnsen A H, Grande P, Zannis V I, Tybjaerg-Hansen A

Abstract excerpt

OBJECTIVES: To determine whether mutations in APOA1 affect levels of high-density lipoprotein (HDL) cholesterol and to predict risk of ischaemic heart disease (IHD) and total mortality in the general population. BACKGROUND: Epidemiologically, risk of IHD is inversely related to HDL cholesterol levels. Mutations in apolipoprotein (apo) A-I, the major protein constituent of HDL, might be associated with low HDL...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21443680
DOI: 10.1111/j.1365-2796.2011.02381.x

Genes

APOA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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