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Article

Polymorphism in APOB associated with increased low-density lipoprotein levels in both genders in the general population.

The Journal of clinical endocrinology and metabolism - 1 Oct 2005

Benn Marianne, Nordestgaard Børge G, Jensen Jan S, Grande Peer, Sillesen Henrik, Tybjaerg-Hansen Anne

Abstract excerpt

CONTEXT: Rare mutations in APOB cause hypercholesterolemia. Whether common polymorphisms in APOB have similar effects remains controversial. OBJECTIVE: We tested the hypothesis that the APOB 7673C>T polymorphism (T2488T) is associated with variation in low-density lipoprotein (LDL) levels and with risk of ischemic heart disease (IHD), ischemic cerebrovascular disease (ICVD), and total mortality in the general...

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Source

Identifiers

PMID: 16030169
DOI: 10.1210/jc.2005-0974

Genes

APOB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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