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Article

The expression of p75 neurotrophin receptor protects against the neurotoxicity of soluble oligomers of beta-amyloid.

Experimental cell research - 15 Nov 2005

Costantini Claudio, Della-Bianca Vittorina, Formaggio Elena, Chiamulera Christian, Montresor Alessio, Rossi Filippo

Abstract excerpt

In this paper, evidence is provided that p75 neurotrophin receptor (p75NTR) exerts an opposite role on the cytotoxic function of beta-amyloid (Abeta) depending on the different state of the peptide, fibrillar or oligomeric soluble form. Previous work in our laboratory has shown that the expression of p75NTR is required for cell death in vitro by Abeta peptides in fibrillar form (G. Perini, V. Della-Bianca, V....

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Identifiers

PMID: 16223482
DOI: 10.1016/j.yexcr.2005.09.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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