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Article

Neurotrophins and neurodegeneration

27 May 2003

Abstract excerpt

There is growing evidence that reduced neurotrophic support is a significant factor in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS). In this review we discuss the structure and functions of neurotrophins such as nerve growth factor, and the role of these proteins and their tyrosine kinase (Trk) receptors in the...

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Identifiers

PMID: 12787319
DOI: 10.1046/j.1365-2990.2003.00487.x

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