Article
The Candida albicans vacuole is required for differentiation and efficient macrophage killing.
Eukaryotic cell - 1 Oct 2005
Palmer G E, Kelly M N, Sturtevant J E
Abstract excerpt
Yeast-hypha differentiation is believed to be necessary for the normal progression of Candida albicans infections. The emergence and extension of a germ tube from a parental yeast cell are accompanied by dynamic changes in vacuole size and morphology. Although vacuolar function is required during this process, it is unclear if it is vacuolar expansion or some other vacuolar function that is important. We...
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