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The putative vacuolar ATPase subunit Vma7p of Candida albicans is involved in vacuole acidification, hyphal development and virulence.

Microbiology (Reading, England) - 1 May 2005

Poltermann Sophia, Nguyen Monika, Günther Juliane, Wendland Jürgen, Härtl Albert, Künkel Waldemar, Zipfel Peter F, Eck Raimund

Abstract excerpt

The vacuolar H+-ATPase (V-ATPase) component Vma7p of the human-pathogenic yeast Candida albicans regulates hyphal growth induced by serum and Spider medium and is essential for virulence. In order to characterize the functions of the putative V-ATPase subunit Vma7p of C. albicans, null mutants were generated. The resulting mutants showed reduced vacuole acidification, which correlated with defective growth at...

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PMID: 15870472
DOI: 10.1099/mic.0.27505-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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