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Article

Contribution of VMA5 to vacuolar function, stress response, ion homeostasis and autophagy in Candida albicans.

Future microbiology - 1 Oct 2017

Zhang Kai, Jia Chang, Yu Qilin, Xiao Chenpeng, Dong Yijie, Zhang Meng, Zhang Dan, Zhao Qiang, Zhang Biao, Li Mingchun

Abstract excerpt

AIM: V-ATPase is a conservative multi-subunit enzyme in eukaryotes and modulates several cellular responses. This study aimed to illustrate the roles of Vma5 in vacuolar function, oxidative stress response, calcium homeostasis, autophagy and virulence. MATERIALS & METHODS: The vma5Δ/Δ mutant was obtained using PCR-mediated homologous recombination. The functions of Vma5 were investigated by a series of...

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PMID: 28879785
DOI: 10.2217/fmb-2017-0029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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