Article
Candida albicans VAC8 is required for vacuolar inheritance and normal hyphal branching.
Eukaryotic cell - 1 Feb 2006
Barelle Caroline J, Richard Mathias L, Gaillardin Claude, Gow Neil A R, Brown Alistair J P
Abstract excerpt
Hyphal growth is prevalent during most Candida albicans infections. Current cell division models, which are based on cytological analyses of C. albicans, predict that hyphal branching is intimately linked with vacuolar inheritance in this fungus. Here we report the molecular validation of this model, showing that a specific mutation that disrupts vacuolar inheritance also affects hyphal division. The armadillo...
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