Article
Roles of VPH2 and VMA6 in localization of V-ATPase subunits, cell wall functions and filamentous development in Candida albicans.
Fungal genetics and biology : FG & B - 1 May 2018
Jia Chang, Zhang Kai, Zhang Dan, Yu Qilin, Zhao Qiang, Xiao Chenpeng, Dong Yijie, Chu Maoping, Li Mingchun
Abstract excerpt
The vacuolar-type H+-ATPase (V-ATPase) is known to be associated with various cellular processes. Several V-ATPase subunits have been identified in C. albicans. However, there are still a few V-ATPase subunits and assembly factors that remain uncharacterized. In this study, we identified one of putative V-ATPase assembly factors, Vph2, and V0 subunit, Vma6, and explored their potential functions in C. albicans....
Topics
- Animals
- Candida albicans
- Cell Wall
- Endocytosis
- Female
- Fungal Proteins
- Hyphae
- Membrane Proteins
- Mice
- Mice, Inbred ICR
- Mutation
- Protein Subunits
- Vacuolar Proton-Translocating ATPases
- Vacuoles