Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development of depression: sex and the interaction between environment and a promoter polymorphism of the serotonin transporter gene.

The international journal of neuropsychopharmacology - 1 Aug 2006

Sjöberg Rickard L, Nilsson Kent W, Nordquist Niklas, Ohrvik John, Leppert Jerzy, Lindström Leif, Oreland Lars

Abstract excerpt

Previous research has demonstrated that a polymorphism in the serotonin transporter gene (5-HTTLPR) and adverse psychosocial circumstances interact to predict depression. The purpose of the present study was to explore the extent to which sex modulates these effects. Eighty-one boys and 119 girls (16-19 years old) were interviewed about psychosocial background variables and genotyped for the 5-HTT promoter...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Share to Serotonin Plasma Membrane Transport Proteins

Share to Sex Characteristics

Share to Social Environment

Source

Identifiers

PMID: 16212676
DOI: 10.1017/S1461145705005936

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development of depression: sex and the interaction between environment and a promoter polymorphism of the serotonin transporter gene.PMID 16212676Read ↗

Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene.Semantic proximity Read ↗

Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR).Semantic proximity Read ↗

Early family environment, current adversity, the serotonin transporter promoter polymorphism, and depressive symptomatology.Semantic proximity Read ↗

The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis.Semantic proximity Read ↗

5-HTTLPR X stress in adolescent depression: moderation by MAOA and gender.Semantic proximity Read ↗

Gender differences in the genetic and environmental determinants of adolescent depression.Semantic proximity Read ↗

Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis.Semantic proximity Read ↗

Sometimes It's Good to be Short: The Serotonin Transporter Gene, Positive Parenting, and Adolescent Depression.Semantic proximity Read ↗

Gene-environment interactions predict cortisol responses after acute stress: implications for the etiology of depression.Semantic proximity Read ↗

Interaction between the 5-HTTLPR serotonin transporter polymorphism and environmental adversity for mood and anxiety psychopathology: evidence from a high-risk community sample of young adults.Semantic proximity Read ↗

Interaction of serotonin transporter gene-linked polymorphic region and stressful life events predicts cortisol stress response.Semantic proximity Read ↗

Effects of genetic and early environmental risk factors for depression on serotonin transporter expression and methylation profiles.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.