Article
Interaction between the 5-HTTLPR serotonin transporter polymorphism and environmental adversity for mood and anxiety psychopathology: evidence from a high-risk community sample of young adults.
The international journal of neuropsychopharmacology - 1 Jul 2009
Laucht Manfred, Treutlein Jens, Blomeyer Dorothea, Buchmann Arlette F, Schmid Brigitte, Becker Katja, Zimmermann Ulrich S, Schmidt Martin H, Esser Günter, Rietschel Marcella, Banaschewski Tobias
Abstract excerpt
Previous research examining gene-environment interaction (GxE) with regard to vulnerability to depression and anxiety has yielded conflicting results. The present study was designed to further investigate GxE between 5-HTTLPR and exposure to environmental adversity, using different phenotypic and genotypic characterizations as well as different types of adversity within a prospective study design. Data were...
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