Article
Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR).
Behavior genetics - 1 Jan 2008
Brummett Beverly H, Boyle Stephen H, Siegler Ilene C, Kuhn Cynthia M, Ashley-Koch Allison, Jonassaint Charles R, Züchner Stephan, Collins Ann, Williams Redford B
Abstract excerpt
The short (s) variant of the serotonin transporter (5-HTT) gene linked functional polymorphic region (5-HTTLPR) is associated with depression. Stressful life events, gender, and race have been shown to moderate this association. We examined the relationship between 5-HTTLPR genotype and symptoms of depression in two samples. Study 1 = 288 participants from a study of caregiver stress; and Study 2 = 142...
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