Article
Human parainfluenza virus 3 neuraminidase activity contributes to dendritic cell maturation.
Viral immunology - 1 Jan 2005
Horga Maria-Arantxa, Macip Salvador, Tuyama Ana C, Tan Maria C, Gusella G Luca
Abstract excerpt
Mechanisms of dendritic cells (DCs) immunomodulation by parainfluenza viruses have not been characterized. We analyzed whether the human parainfluenza 3 (HPF3) virus hemagglutinin-neuraminidase glycoprotein (HN) might influence DC maturation. HN possesses a receptor binding function and a neuraminidase or desialidating activity. To assess whether the neuraminidase activity of HN affects DC maturation, human...
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