Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cysteinyl leukotrienes in allergic inflammation: strategic target for therapy.

Chest - 1 Apr 2005

Busse William, Kraft Monica

Abstract excerpt

Systemically bioavailable leukotriene receptor antagonists (LTRAs) can reduce the essential components of allergic inflammation in allergic rhinitis (AR) and asthma by blocking cysteinyl leukotriene (CysLT) activity, resulting in a wide range of clinical effects. CysLTs, mediators, and modulators in the pathophysiology of asthma and AR are a key target for therapy because they modulate production of hemopoietic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Cysteine
Share to Hypersensitivity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammation Mediators

Share to Leukotrienes

Share to Phenotype

Share to Quality of Life

Share to Rhinitis, Allergic, Perennial

Source

Identifiers

PMID: 15821210
DOI: 10.1378/chest.127.4.1312

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cysteinyl leukotrienes in allergic inflammation: strategic target for therapy.PMID 15821210Read ↗

Cysteinyl‐leukotrienes and their receptors in asthma and other inflammatory diseases: Critical update and emerging trendsSemantic proximity Read ↗

Leukotriene pathway genetics and pharmacogenetics in allergySemantic proximity Read ↗

Update on recent advances in the management of aspirin exacerbated respiratory disease.Semantic proximity Read ↗

Effects of non-steroidal anti-inflammatory drugs and other eicosanoid pathway modifiers on antiviral and allergic responses. EAACI task force on eicosanoids consensus report in times of COVID-19Semantic proximity Read ↗

Aspirin or other nonsteroidal inflammatory agent exacerbated asthma.Semantic proximity Read ↗

Functional Characterization of Human Cysteinyl Leukotriene 1 Receptor Gene StructureSemantic proximity Read ↗

G-protein-coupled receptors and asthma endophenotypes: the cysteinyl leukotriene system in perspective.Semantic proximity Read ↗

Expression of the cysteinyl leukotriene receptors cysLT(1) and cysLT(2) in aspirin-sensitive and aspirin-tolerant chronic rhinosinusitis.Semantic proximity Read ↗

Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association StudiesSemantic proximity Read ↗

Upper airways in aspirin-exacerbated respiratory disease.Semantic proximity Read ↗

Allergy, Allergic Inflammation and Asthma--Keystone Symposium. Pharmacological targets in allergic inflammation and asthma.Semantic proximity Read ↗

Nitric oxide: a major determinant of mast cell phenotype and function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.