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Article

The genetic contribution and relevance of knee cartilage defects: case-control and sib-pair studies.

The Journal of rheumatology - 1 Oct 2005

Ding Changhai, Cicuttini Flavia, Scott Fiona, Stankovich James, Cooley Helen, Jones Graeme

Abstract excerpt

OBJECTIVE: To describe the differences in knee cartilage defects between offspring of subjects with at least one parent with a total knee replacement for severe primary knee osteoarthritis (OA) and controls; and to estimate the heritability of knee cartilage defects in sib-pairs. METHODS: Population based, case-control study of 186 matched pairs (mean age 45 yrs, range 26-61) and sib-pair study of 128 subjects...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16206350

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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