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Article

The offspring of people with a total knee replacement for severe primary knee osteoarthritis have a higher risk of worsening knee pain over 8 years.

Annals of the rheumatic diseases - 1 Feb 2016

Pan Feng, Ding Changhai, Winzenberg Tania, Khan Hussain, Martel-Pelletier Johanne, Pelletier Jean-Pierre, Cicuttini Flavia, Jones Graeme

Abstract excerpt

OBJECTIVE: To investigate whether offspring having at least one parent with a total knee replacement for severe primary knee osteoarthritis (OA) have an increased risk of worsening knee pain over 8 years as compared with controls with no family history of knee OA. METHODS: A total of 219 participants (mean age 48 years, range 29-61 years) with 115 offspring and 104 controls participated in this study. Knee pain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25475117
DOI: 10.1136/annrheumdis-2014-206005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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