Article
Genetic risk of knee osteoarthritis: a sibling study.
Annals of the rheumatic diseases - 1 Sept 2004
Neame R L, Muir K, Doherty S, Doherty M
Abstract excerpt
OBJECTIVES: To determine whether there is a genetic contribution to knee osteoarthritis (OA) as defined by structural change on plain radiographs. DESIGN: Sibling study. Comparison of knee OA prevalence in the community with knee OA prevalence among siblings of index cases with knee OA. SUBJECTS: 490 knee OA index cases listed for total knee replacement and 737 of their siblings aged >40 years, 1729 community...
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